Cryptic crossword clue
Notice about holding in toxin 8

The most common and most likely answer to this crossword clue is the 8 letter word NICOTINE

I've seen this crossword clue in Financial Times
N
I
C
O
T
I
N
E


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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does NICOTINE mean?

NICOTINE noun
  1. An alkaloid (C10H14N2), commonly occurring in the tobacco plant. In small doses it is a habit-forming stimulant; in larger doses it is toxic and is often used in insecticides.
  2. Tobacco, cigarettes

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