The most common and most likely answer to this crossword clue is the 10 letter word ADMINISTER
A
D
M
I
N
I
S
T
E
R
More clues leading to the result ADMINISTER
- Direct politician on party political broadcast?
- Run around after evacuation with senior politician
- Manage commercial unit in church
- A nurse covering up daughter's conduct
- Provide the Cabinet's publicity man?
- Run corrupt trade importing cars
- Run after Jesus’s birth with man of God
- Give notice to cleric
- I strained muscle at first, going out for run
- Run and puff — clergyman required
Buddy explains!
The straight part
We know that "take charge" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case take charge = administer.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ADMINISTER mean?
ADMINISTER verb- To cause to ingest (a drug), either by openly offering or through deceit.
- To apportion out, distribute.
- To manage or supervise the conduct, performance or execution of; to govern or regulate the parameters for the conduct, performance or execution of; to work in an administrative capacity.
- To minister (to).
- To settle, as the estate of one who dies without a will, or whose will fails of an executor.
- To give, as an oath.
- To give a drug to a patient, be it orally or by any other means.