Cryptic crossword clue
Notice the foam at the mouth 6

The most common and most likely answer to this crossword clue is the 6 letter word SEETHE

I've seen this crossword clue in Financial Times
S
E
E
T
H
E


Buddy explains!

The straight part
We know that "foam at the mouth" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case foam at the mouth = seethe.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SEETHE mean?

SEETHE verb
  1. To boil.
  2. (of a liquid) To boil vigorously.
  3. (of a liquid) To foam in an agitated manner, as if boiling.
  4. (of a person) To be in an agitated or angry mental state, as if boiling.
  5. (of a place) To buzz with activity.

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