The most common and most likely answer to this crossword clue is the 6 letter word HOCKED
H
O
C
K
E
D
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does HOCKED mean?
HOCKED verb- To disable by cutting the tendons of the hock; to hamstring; to hough.
- To leave with a pawnbroker as security for a loan.
- To bother; to pester; to annoy incessantly
- (in combination) Having a specified kind of hock.