Cryptic crossword clue
Novel’s end, novel’s theme

The most common and most likely answer to this crossword clue is the 5 letter word LEMMA

I've seen this crossword clue in The Times
L
E
M
M
A


Buddy explains!

The straight part
We know that "theme" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case theme = lemma.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does LEMMA mean?

LEMMA noun
  1. A proposition proved or accepted for immediate use in the proof of some other proposition.
  2. The canonical form of an inflected word; i.e., the form usually found as the headword in a dictionary, such as the nominative singular of a noun, the bare infinitive of a verb, etc.
  3. (psycholinguistics) The theoretical abstract conceptual form of a word, representing a specific meaning, before the creation of a specific phonological form as the sounds of a lexeme, which may find representation in a specific written form as a dictionary or lexicographic word.
LEMMA noun
  1. The outer shell of a fruit or similar body.
  2. One of the specialized bracts around the floret in grasses.

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