Cryptic crossword clue
Nuclear reactor is a singular source of discomfort 4

The most common and most likely answer to this crossword clue is the 4 letter word PILE

I've seen this crossword clue in The Guardian
P
I
L
E


Buddy explains!

The straight part
We know that "Nuclear reactor/a singular source of discomfort" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case nuclear reactor/a singular source of discomfort = pile.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PILE mean?

PILE noun
  1. A mass of things heaped together; a heap.
  2. A group or list of related items up for consideration, especially in some kind of selection process.
  3. A mass formed in layers.
  4. A funeral pile; a pyre.
  5. A large amount of money.
  6. A large building, or mass of buildings.
  7. A bundle of pieces of wrought iron to be worked over into bars or other shapes by rolling or hammering at a welding heat; a fagot.
  8. A vertical series of alternate disks of two dissimilar metals (especially copper and zinc), laid up with disks of cloth or paper moistened with acid water between them, for producing a current of electricity; a voltaic pile, or galvanic pile.
  9. An atomic pile; an early form of nuclear reactor.
  10. The reverse (or tails) of a coin.
  11. A list or league
PILE verb
  1. (often used with the preposition "up") To lay or throw into a pile or heap; to heap up; to collect into a mass; to accumulate
  2. To cover with heaps; or in great abundance; to fill or overfill; to load.
  3. To add something to a great number.
  4. (of vehicles) To create a hold-up.
  5. To place (guns, muskets, etc.) together in threes so that they can stand upright, supporting each other.
PILE noun
  1. A dart; an arrow.
  2. The head of an arrow or spear.
  3. A large stake, or piece of pointed timber, steel etc., driven into the earth or sea-bed for the support of a building, a pier, or other superstructure, or to form a cofferdam, etc.
  4. One of the ordinaries or subordinaries having the form of a wedge, usually placed palewise, with the broadest end uppermost.
PILE verb
  1. To drive piles into; to fill with piles; to strengthen with piles.
PILE noun
  1. (usually in the plural) A hemorrhoid.
PILE noun
  1. Hair, especially when very fine or short; the fine underfur of certain animals. (Formerly countable, now treated as a collective singular.)
  2. The raised hairs, loops or strands of a fabric; the nap of a cloth.
PILE verb
  1. To give a pile to; to make shaggy.

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