The most common and most likely answer to this crossword clue is the 6 letter word ISOMER
I
S
O
M
E
R
More clues leading to the result ISOMER
- A few occupying Irish compound
- One or two coming into Irish compound
- Compound very like another is more unstable
- Compound interest originally an amount at either end
- Chemical compound is getting Rome fouled up
- Compound is linked to the fall of Rome
- A few locked in centre of firm’s compound
- On the way to this compound, is Rome burned?
- Nuclei some researchers found could be nuclear
- Starting off memoirs about compound
Buddy explains!

The straight part
We know that "could be nuclear" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case could be nuclear = isomer.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ISOMER mean?
ISOMER noun- Any of two or more compounds with the same molecular formula but with different structure.
- Any of two or more atomic nuclei with the same mass number and atomic number but with different radioactive properties.