The most common and most likely answer to this crossword clue is the 10 letter word HARASSMENT
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More clues leading to the result HARASSMENT
- Persecution hurt agreement, with delay of minutes
- Mutant has ten arms: that spells trouble!
- Donkey attendants in deer molestation
- Though unusually smart he’s an annoyance
- Trouble from injury containing clot on hospital department
- Man’s heart’s fluttering? That’s no excuse for this!
- Pestering endlessly cruel man breaking agreement
- Sarah’s turned to men in street in constant intimidation
- Stag gathering: guys who appreciate a bit of cheek and some inappropriate sexual overtures
- Nuisance hurt hospital department holding idiot
Buddy explains!

The straight part
We know that "Nuisance" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case nuisance = harassment.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does HARASSMENT mean?
HARASSMENT noun- Persistent attacks and criticism causing worry and distress.
- Deliberate pestering or annoying.
- Excessive intimidation.