Cryptic crossword clue
Nuisance mentioned on every side in holiday region 10

The most common and most likely answer to this crossword clue is the 10 letter word PLAYGROUND

I've seen this crossword clue in Financial Times
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Buddy explains!

The straight part
We know that "holiday region" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case holiday region = playground.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PLAYGROUND mean?

PLAYGROUND noun
  1. (outdoors) A large open space for children to play on, usually having dedicated play equipment (such as swings and slides).
  2. Any physical or metaphysical space in which a person or organization has free rein to do as they please.

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