Cryptic crossword clue
Nuisance occupying ladies, say 13

The most common and most likely answer to this crossword clue is the 13 letter word INCONVENIENCE

I've seen this crossword clue in The Times
I
N
C
O
N
V
E
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E

Buddy explains!

The straight part
We know that "Nuisance" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case nuisance = inconvenience.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INCONVENIENCE mean?

INCONVENIENCE noun
  1. The quality of being inconvenient.
  2. Something that is not convenient, something that bothers.
INCONVENIENCE verb
  1. To bother; to discomfort

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