Cryptic crossword clue
Numbers overwhelm these whizzes 10

The most common and most likely answer to this crossword clue is the 10 letter word SENSATIONS

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Buddy explains!

The straight part
We know that "Numbers overwhelm these/whizzes" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case numbers overwhelm these/whizzes = sensations.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SENSATIONS mean?

SENSATIONS noun
  1. A physical feeling or perception from something that comes into contact with the body; something sensed.
  2. A widespread reaction of interest or excitement.

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