The most common and most likely answer to this crossword clue is the 6 letter word ISSUES
I
S
S
U
E
S
More clues leading to the result ISSUES
- Iceland makes legal claim — controversial matters
- Matters for debate in periodical publications
- . Supplies paper handkerchiefs to wipe head
- Problems in editions?
- Comes out as terrorist group takes legal action
- Problems with kids and spouses primarily
- Matters for discussion in publications
- Children produced periodically
- Concerns — lots of little ones raised by partners, normally
- See 6dn.
Buddy explains!

The straight part
We know that "Numbers/topics" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case numbers/topics = issues.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ISSUES mean?
ISSUES noun- The action or an instance of flowing or coming out, an outflow, particularly:
- Someone or something that flows out or comes out, particularly:
- The means or opportunity by which something flows or comes out, particularly:
- The place where something flows or comes out, an outlet, particularly:
- The action or an instance of sending something out, particularly:
- Any question or situation to be resolved, particularly:
- The action or an instance of concluding something, particularly:
- The end result of an event or events, any result or outcome, particularly:
- The action or an instance of feeling some emotion.
- The action or an instance of leaving any state or condition.
- To flow out, to proceed from, to come out or from.
- To rush out, to sally forth.
- To extend into, to open onto.
- To turn out in a certain way, to result in.
- To come to a point in fact or law on which the parties join issue.
- To send out; to put into circulation.
- To deliver for use.
- To deliver by authority.