Cryptic crossword clue
Numbing cold crushing Scott's heart, Amundsen ultimately coming first 8

The most common and most likely answer to this crossword clue is the 8 letter word NARCOTIC

I've seen this crossword clue in The Times
N
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Buddy explains!

The straight part
We know that "Numbing" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case numbing = narcotic.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does NARCOTIC mean?

NARCOTIC noun
  1. Any substance or drug that reduces pain, induces sleep and may alter mood or behaviour; in some contexts, especially in reference to the opiates-and-opioids class, especially in reference to illegal drugs, and often both.
  2. Any type of numbing drug.
NARCOTIC adjective
  1. Of, or relating to narcotics.
  2. (pharmaceutical effect) Inducing sleep; causing narcosis.

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