Cryptic crossword clue
Nurse to leave bed in medical drama: it softens the flesh 10

The most common and most likely answer to this crossword clue is the 10 letter word TENDERISER

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "it softens the flesh" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case it softens the flesh = tenderiser.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does TENDERISER mean?

TENDERISER noun
  1. Any substance added to meat before cooking in order to make it more tender, especially any source of the enzyme papain
  2. A form of mallet used to beat meat before cooking

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