The most common and most likely answer to this crossword clue is the 8 letter word ENORMOUS
I've seen this crossword clue in The Guardian
E
N
O
R
M
O
U
S
More clues leading to the result ENORMOUS
- Rodent leading with its tail, and not very big
- Huge tailless rodent follows one around river
- Very fat figure turns and runs before sumo wrestling
- Unit picked up Republican on second Yankee jumbo
- Like big creature and not small one, with tail raised
- Rising endlessly, Finland’s river, one that’s vast
- Doctor sure moon is huge
- Huge portion of chicken or moussaka
- Exercising our men, so they become really big
- Giant turns sour on me
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ENORMOUS mean?
ENORMOUS adjective- Deviating from the norm; unusual, extraordinary.
- Exceedingly wicked; atrocious or outrageous.
- Extremely large; greatly exceeding the common size, extent, etc.