The most common and most likely answer to this crossword clue is the 4 letter word MUST
M
U
S
T
More clues leading to the result MUST
- Stone in French museum not to be missed
- Unmissable stone in French museum
- Has to put out Money for Nothing
- Set viewing flash Meteor Eye uses
- Meets us in transit for an essential event
- Frenzy brought by smell of dampness
- Obligatory cover-up hurts umpire
- Essential element of returned contract summarised in part
- Mould stum?
- Has to be new wine
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does MUST mean?
MUST noun- Something that is mandatory or required.
- (modal auxiliary, defective) To do with certainty; indicates that the speaker is certain that the subject will have executed the predicate.
- (modal auxiliary, defective) To do as a requirement; indicates that the sentence subject is required as an imperative or directive to execute the sentence predicate, with failure to do so resulting in a negative consequence.
- (modal auxiliary, defective) said about something that is very likely, probable, or certain to be true
- The property of being stale or musty.
- Something that exhibits the property of being stale or musty.
- Fruit juice that will ferment or has fermented, usually from grapes.
- To make musty.
- To become musty.
- A time during which male elephants exhibit increased levels of sexual activity and aggressiveness (also spelled musth).
- An elephant in this sexual and aggressive state.