The most common and most likely answer to this crossword clue is the 10 letter word COMMITMENT
I've seen this crossword clue in The Guardian
C
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M
M
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T
M
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T
More clues leading to the result COMMITMENT
- Remark about US university’s dedication
- Observation about retired chap’s loyalty
- Remark about American university’s dedication
- Promise loyalty
- Something the can be avoided by confirmed bachelors in their right minds?
- Dedication of US university evident in discussion
- Remark about German with loyalty
- Promise loyalty
- Remark written about university duty
- Order to go down note containing appeal requiring money
Buddy explains!

The straight part
We know that "loyalty" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case loyalty = commitment.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does COMMITMENT mean?
COMMITMENT noun- The act or an instance of committing, putting in charge, keeping, or trust, especially:
- Promise or agreement to do something in the future, especially:
- Being bound emotionally or intellectually to a course of action or to another person or persons.
- The trait of sincerity and focused purpose.
- Perpetration as in a crime or mistake.
- State of being pledged or engaged.
- The act of being locked away, such as in an institution for the mentally ill or in jail.