Cryptic crossword clue
Odd bod and I agreed to break up, naturally 10

The most common and most likely answer to this crossword clue is the 10 letter word BIODEGRADE

I've seen this crossword clue in The Times
B
I
O
D
E
G
R
A
D
E

Buddy explains!

The straight part
We know that "break up, naturally" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case break up, naturally = biodegrade.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BIODEGRADE mean?

BIODEGRADE verb
  1. To decompose as a result of biological action, especially by microorganisms

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