Cryptic crossword clue
Odd men out, sirs sadly taken amiss 13

The most common and most likely answer to this crossword clue is the 13 letter word MISUNDERSTOOD

I've seen this crossword clue in The Daily Telegraph
M
I
S
U
N
D
E
R
S
T
O
O
D

Buddy explains!

The straight part
We know that "taken amiss" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case taken amiss = misunderstood.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MISUNDERSTOOD mean?

MISUNDERSTOOD verb
  1. To understand incorrectly, while believing one has understood correctly.

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