Cryptic crossword clue
Oddly cruel play beginning to irritate fans 10

The most common and most likely answer to this crossword clue is the 10 letter word PECULIARLY

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Buddy explains!

The straight part
We know that "Oddly" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case oddly = peculiarly.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PECULIARLY mean?

PECULIARLY adverb
  1. Such as to be greater than usual; particularly; exceptionally.
  2. Such as to be strange or odd.
  3. Strongly associated with.

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