Cryptic crossword clue
Oddly, loner awash, swimming with toothy mammals

The most common and most likely answer to this crossword clue is the 8 letter word NARWHALS

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Buddy explains!

The straight part
We know that "toothy mammals" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case toothy mammals = narwhals.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does NARWHALS mean?

NARWHALS noun
  1. Monodon monoceros, an Arctic cetacean that grows to about 20 feet (6 meters) long, the male having a single horn-like tusk, a twisted, pointed canine tooth that projects forward.

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