Cryptic crossword clue
Odie, at first sounding lupine, is now following commands 7

The most common and most likely answer to this crossword clue is the 7 letter word OBEYING

O
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Buddy explains!

The straight part
We know that "following commands" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case following commands = obeying.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does OBEYING mean?

OBEYING verb
  1. To do as ordered by (a person, institution etc), to act according to the bidding of.
  2. To do as one is told.
  3. To be obedient, compliant (to a given law, restriction etc.).

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