Cryptic crossword clue
Of course, having been in tune, first of discords dreadful 4,7

The most common and most likely answer to this crossword clue is the 4 plus 7 letter word BIEN ENTENDU

I've seen this crossword clue in The Times
B
I
E
N
E
N
T
E
N
D
U

Buddy explains!

The straight part
We know that "Of course" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case of course = bien entendu.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

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