Cryptic crossword clue
Oily and obsequious Spanish interjection involving nothing anti-American 10

The most common and most likely answer to this crossword clue is the 10 letter word OLEAGINOUS

I've seen this crossword clue in Financial Times
O
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Buddy explains!

The straight part
We know that "Oily/obsequious" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case oily/obsequious = oleaginous.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does OLEAGINOUS mean?

OLEAGINOUS adjective
  1. Oily, greasy.
  2. (of manner or speech) Falsely or affectedly earnest; persuasively suave.

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