Cryptic crossword clue
Old lady worried, entering empty manor 5

The most common and most likely answer to this crossword clue is the 5 letter word MATER

I've seen this crossword clue in Independent
M
A
T
E
R

Buddy explains!

The straight part
We know that "Old lady" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case old lady = mater.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MATER mean?

MATER noun
  1. Mother.
  2. A meninx; the dura mater, arachnoid mater, or pia mater of the brain.
MATER noun
  1. Someone or something that mates.
MATER noun
  1. Tomato.

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