The most common and most likely answer to this crossword clue is the 6 letter word TITANS
I've seen this crossword clue in The Daily Telegraph
T
I
T
A
N
S
More clues leading to the result TITANS
- Powerful people settle back to ring Brown
- This regularly thrashes giants
- Intellectual greats giving stupid person curt response?
- Old masters neglecting one group of gods
- Model turns up hugging brown giants
- Cronus et al. in a conniption about holding pair from Tarsus hostage
- Giants and Browns interrupted by The Thing
- Oral contracts issue from Uranus
- Originally, Tethys, Iapetus, Theia and nine siblings?
Buddy explains!

The straight part
We know that "group of gods" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case group of gods = titans.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does TITANS mean?
TITANS noun- Something or someone of very large stature, greatness, or godliness.