Cryptic crossword clue
Old, old Asian brought up a problem with fluid 6

The most common and most likely answer to this crossword clue is the 6 letter word OEDEMA

I've seen this crossword clue in The Times
O
E
D
E
M
A

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The straight part
We know that "problem with fluid" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case problem with fluid = oedema.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does OEDEMA mean?

OEDEMA noun
  1. An excessive accumulation of serum in tissue spaces or a body cavity
  2. A similar swelling in plants caused by excessive accumulation of water

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