Cryptic crossword clue
Old rebel who initiates drugs bust in a hospital? 6

The most common and most likely answer to this crossword clue is the 6 letter word ANARCH

I've seen this crossword clue in The Guardian
A
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A
R
C
H

Buddy explains!

The straight part
We know that "Old rebel" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case old rebel = anarch.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ANARCH mean?

ANARCH noun
  1. The author of anarchy; one who excites revolt.

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