Cryptic crossword clue
Old woman has instrument, conceding victory over attempt to worship the saints 10

The most common and most likely answer to this crossword clue is the 10 letter word HAGIOLATRY

I've seen this crossword clue in Financial Times
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Buddy explains!

The straight part
We know that "to worship the saint" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case to worship the saint = hagiolatry.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HAGIOLATRY mean?

HAGIOLATRY noun
  1. The worship of saints.

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