Cryptic crossword clue
Old woman injecting drug to numb bone marrow

The most common and most likely answer to this crossword clue is the 7 letter word MEDULLA

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The cryptic/wordplay part
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This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
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What does MEDULLA mean?

MEDULLA noun
  1. The soft inner part of something, especially the pith of a fruit.
  2. The inner substance of various organs and structures, especially the marrow of bones.
  3. The medulla oblongata.
  4. The internal tissue of a plant.

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