Cryptic crossword clue
On going in opposite directions, best to be persistent 3-4

The most common and most likely answer to this crossword clue is the 7 letter word NONSTOP

I've seen this crossword clue in The Daily Telegraph
N
O
N
S
T
O
P


Buddy explains!

The straight part
We know that "persistent" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case persistent = nonstop.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does NONSTOP mean?

NONSTOP noun
  1. (travel) A nonstop journey, especially a nonstop flight.
  2. A convenience store in parts of Europe, open 24 hours a day.
  3. A linguistic sound that is not a stop; a continuant.
NONSTOP adjective
  1. Without stopping; without interruption or break.
  2. Describing a point mutation within a stop codon that causes the continued translation of an mRNA strand.
NONSTOP adverb
  1. Without stopping; without interruption or break

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