The most common and most likely answer to this crossword clue is the 7 letter word BREWERY
I've seen this crossword clue in The Times
B
R
E
W
E
R
Y
Buddy explains!

The straight part
We know that "manufactured here?" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case manufactured here? = brewery.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does BREWERY mean?
BREWERY noun- A building where beer is produced.
- A company that brews beer.