Cryptic crossword clue
On sides of bottle, a drop formed of high alcoholic content 4-5

The most common and most likely answer to this crossword clue is the 10 letter word BEAD-PROOF

I've seen this crossword clue in The Guardian
B
E
A
D
-
P
R
O
O
F

Buddy explains!

The straight part
We know that "high alcoholic content" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case high alcoholic content = bead-proof.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

Crossword Answer definitions


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