Cryptic crossword clue
On trip with mate, one stops Henry showing too much cheek 12

The most common and most likely answer to this crossword clue is the 12 letter word HONEYMOONING

I've seen this crossword clue in The Guardian
H
O
N
E
Y
M
O
O
N
I
N
G

Buddy explains!

The straight part
We know that "On trip with mate" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case on trip with mate = honeymooning.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HONEYMOONING mean?

HONEYMOONING verb
  1. To have a honeymoon (a trip taken by a couple after wedding).
HONEYMOONING adjective
  1. (of a married couple) On a honeymoon

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