The most common and most likely answer to this crossword clue is the 12 letter word READDRESSING
I've seen this crossword clue in The Times
R
E
A
D
D
R
E
S
S
I
N
G
More clues leading to the result READDRESSING
Buddy explains!
The straight part
We know that "Once again tackling" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case once again tackling = readdressing.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does READDRESSING mean?
READDRESSING verb- To address or deal with again.
- To change the address of.
- The changing of an address.