Cryptic crossword clue
Once vigorous son is certainly not inspiring 7

The most common and most likely answer to this crossword clue is the 7 letter word EXHALES

I've seen this crossword clue in The Guardian
E
X
H
A
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Buddy explains!

The straight part
We know that "is certainly not inspiring" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case is certainly not inspiring = exhales.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EXHALES mean?

EXHALES verb
  1. To expel air from the lungs through the nose or mouth by action of the diaphragm, to breathe out.
  2. To expel (something, such as tobacco smoke) from the lungs by action of the diaphragm.
  3. To pass off in the form of vapour; to emerge.
  4. To emit (a vapour, an odour, etc.).
  5. To draw out; to cause to be emitted in vapour.

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