Cryptic crossword clue
One after drug going through coats, where delicate lifting is required? 10

The most common and most likely answer to this crossword clue is the 10 letter word SPILLIKINS

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Buddy explains!

The straight part
We know that "where delicate lifting is required?" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case where delicate lifting is required? = spillikins.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SPILLIKINS mean?

SPILLIKINS noun
  1. One of the straws (or small pieces of wood, ivory, etc.) used in the game of jackstraws or spillikins.
SPILLIKINS noun
  1. A game in which players attempt to remove flat, carved sticks of ivory or wood (the individual spillikins of meaning 1.) from a scattered pile without disturbing any stick other than the one currently being removed.

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