Cryptic crossword clue
One aloft climbing Andean plateau 4

The most common and most likely answer to this crossword clue is the 4 letter word PUNA

P
U
N
A

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The straight part
We know that "Andean plateau" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case andean plateau = puna.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PUNA mean?

PUNA noun
  1. An alpine biological community in the central portion of the Andes in which short, coarse grass supports a Native American population.

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