Cryptic crossword clue
One bee penetrating flower for something sugary 6

The most common and most likely answer to this crossword clue is the 6 letter word RIBOSE

I've seen this crossword clue in The Guardian
R
I
B
O
S
E

Buddy explains!

The straight part
We know that "something sugary" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case something sugary = ribose.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RIBOSE mean?

RIBOSE noun
  1. A naturally occurring pentose sugar, which is a component of the nucleosides and nucleotides that constitute the nucleic acid biopolymer, RNA. It is also found in riboflavin.

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