Cryptic crossword clue
One billionth newborn a national obsession, primarily 4

The most common and most likely answer to this crossword clue is the 4 letter word NANO

N
A
N
O

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The straight part
We know that "One billionth" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case one billionth = nano.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does NANO mean?

NANO noun
  1. Nanotechnology.

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