Cryptic crossword clue
One cancels new diplomatic mission after leader pulls out 8

The most common and most likely answer to this crossword clue is the 8 letter word NEGATION

I've seen this crossword clue in Independent
N
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The cryptic/wordplay part
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This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
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What does NEGATION mean?

NEGATION noun
  1. The act of negating something.
  2. A denial or contradiction.
  3. A proposition which is the contradictory of another proposition and which can be obtained from that other proposition by the appropriately placed addition/insertion of the word "not". (Or, in symbolic logic, by prepending that proposition with the symbol for the logical operator "not".)
  4. The logical operation which obtains such (negated) propositions.

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