Cryptic crossword clue
One drawing up list of staff protecting old African leader 8

The most common and most likely answer to this crossword clue is the 8 letter word ANIMATOR

A
N
I
M
A
T
O
R


Buddy explains!

The straight part
We know that "One drawing" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case one drawing = animator.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ANIMATOR mean?

ANIMATOR noun
  1. One who animates something; one who brings something to life or the appearance of life.
  2. One who creates an animation or cartoon; a cartoonist.

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