The most common and most likely answer to this crossword clue is the 7 letter word CURATOR
I've seen this crossword clue in The Times
C
U
R
A
T
O
R
More clues leading to the result CURATOR
- Looking up schedule: old police superintendent
- Conservative speaker losing head, grabbing university steward
- Abrupt old Republican ringing a museum boss
- Blunt men taking in a museum keeper
- One in charge having dog roll over
- List former police force sent around seen in Guardian
- Keeper of dog for men
- Museum manager‘s almost rude about schedule
- Copper and informant – or superintendent
- Keeper‘s dog eats rodent and duck
Buddy explains!

The straight part
We know that "One in charge" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case one in charge = curator.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does CURATOR mean?
CURATOR noun- A person who manages, administers or organizes a collection, either independently or employed by a museum, library, archive or zoo.
- One appointed to act as guardian of the estate of a person not legally competent to manage it, or of an absentee; a trustee.
- A member of a curatorium, a board for electing university professors, etc.