The most common and most likely answer to this crossword clue is the 5 letter word GUILT
I've seen this crossword clue in Independent
G
U
I
L
T
More clues leading to the result GUILT
- Sound investment may be shown in court
- Union leader stabs young sow? Shame!
- Remorse of GI after pinching uniform left just outside
- Resembling gold. Containing uranium. Shame
- One Liberal assuming instinctive responsibility
- Shame only valuable on the surface, we hear?
- Criminality shining brightly, we hear?
- Bad feeling caused by tip of instrument left in stomach
- Clear about the Italian’s culpability
- Security around university that may make someone blush
Buddy explains!

The straight part
We know that "responsibility" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case responsibility = guilt.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does GUILT mean?
GUILT noun- Responsibility for wrongdoing.
- The state of having been found guilty or admitted guilt in legal proceedings.
- The regret of having done wrong.
- To commit offenses; act criminally.
- To cause someone to feel guilt, particularly in order to influence their behaviour.