Cryptic crossword clue
One looks for mine to do well without time in company 10

The most common and most likely answer to this crossword clue is the 10 letter word PROSPECTOR

I've seen this crossword clue in The Times
P
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P
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Buddy explains!

The straight part
We know that "One looks for mine" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case one looks for mine = prospector.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PROSPECTOR mean?

PROSPECTOR noun
  1. A person who explores or prospects an area in search of mineral deposits, such as gold.

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