Cryptic crossword clue
One radical answer to stop clever men and beat regulator 13

The most common and most likely answer to this crossword clue is the 13 letter word DEFIBRILLATOR

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Buddy explains!

The straight part
We know that "beat regulator" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case beat regulator = defibrillator.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DEFIBRILLATOR mean?

DEFIBRILLATOR noun
  1. An electronic device used internally or externally that delivers a controlled electric shock to a patient to correct ventricular fibrillation, a lack of coordination of the contraction of muscle tissue of the large chambers of the heart.

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