Cryptic crossword clue
One ruining the enjoyment of others overindulges on drink

The most common and most likely answer to this crossword clue is the 10 letter word SPOILSPORT

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "One ruining the enjoyment of others" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case one ruining the enjoyment of others = spoilsport.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SPOILSPORT mean?

SPOILSPORT noun
  1. Someone who puts an end to others' fun, especially harmless fun.
SPOILSPORT adjective
  1. Like a spoilsport.

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