Cryptic crossword clue
One that mistreated a table-cleaner's son — thrown out 6

The most common and most likely answer to this crossword clue is the 6 letter word ABUSER

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Buddy explains!

The straight part
We know that "One that mistreated" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case one that mistreated = abuser.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ABUSER mean?

ABUSER noun
  1. One who abuses someone or something.
  2. One who uses in an illegal or wrongful use.

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