Cryptic crossword clue
One unpleasant person outside work, one with fourteen members 6

The most common and most likely answer to this crossword clue is the 6 letter word ISOPOD

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "one with fourteen members" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case one with fourteen members = isopod.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ISOPOD mean?

ISOPOD noun
  1. Any of very many crustaceans, of the order Isopoda, that have a flattened body and no carapace.

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