Cryptic crossword clue
One with constituency in city house – she has irresistible urges 6

The most common and most likely answer to this crossword clue is the 6 letter word NYMPHO

N
Y
M
P
H
O


Buddy explains!

The straight part
We know that "she has irresistible urges" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case she has irresistible urges = nympho.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does NYMPHO mean?

NYMPHO verb
  1. To become obsessed about sex.
NYMPHO noun
  1. A woman with an excessive libido.

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